If you have multiple monitors you will want to move your mouse and desktop items across the screen diagonally from one monitor to the other in the direction that you choose.

So how do you do this.

Right click on your desktop and go to " personalize"

or go to Control Panel and open" Personalization"

Click on Display

Click Change display settings

You will now see your 2 monitors labeled 1 & 2 .

To alter the position and the way you move items on your desktop just click on the monitor on the screen and drag to the other side of the monitor

 
You can now rearrange the monitors to accommodate the way you want to work on your screens.

When you have finished arranging the screens , just click apply.